Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Sep 2019
[Epidemiological comparison between the new and the old diagnostic criteria for sepsis: a retrospective cohort study based on the database of Beijing Public Health Information System].
To describe and compare the epidemiology of Sepsis-1 and Sepsis-3 in Yuetan Subdistrict of Beijing, and to estimate the incidence of Sepsis-3 in China. ⋯ Male, elder, more comorbidities and low BMI were risk factors for sepsis. The standardized incidence of Sepsis-3 in Yuetan Subdistrict of Beijing was 236 per 100 000 person-year, and speculated there were 2.5 million new cases of Sepsis-3 per year, resulting in more than 700 000 deaths in China. According to the diagnostic criterion of Sepsis-3, 2.36 million new cases per year were reduced, and the mortality was increased by 11.4%, as compared with the criterion of Sepsis-1.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Sep 2019
[Expressions of CD4+CD45RA+T cells and CD4+CD45RO+T cells in peripheral blood of patients with acute coronary syndrome and their significance].
To investigate the expressions of CD4+CD45RA+T cells and CD4+CD45RO+T cells in peripheral blood of patients with acute coronary syndrome (ACS) and their significance. ⋯ There was no significant difference in the ratio of CD4+CD45RA+T cells among UAP, NSTEMI and STEMI patients, and CD4+CD45RO+T cells ratio in the STEMI group was significantly lower than that in the UAP group and NSTEMI group. CD4+CD45RO+T cells ratio may be risk factor of STEMI.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Sep 2019
[Application of modified microbubble test in peripherally inserted central venous catheters tip positioning].
To analyze the specificity and sensitivity of the modified microbubble test in identifying the peripherally inserted central venous catheters (PICC) tip based on the chest X-ray location as the "gold standard", and to find out an accurate and noninvasive PICC tip positioning method that can save time and cost. ⋯ Compared with the chest X-ray localization method, the modified microbubble test method has high sensitivity and specificity in identifying PICC in the position, and the operation is simple, noninvasive, with less time and low cost. The modified microbubble test can be used as a screening test for PICC tip position, especially in ICU. When there are technical limitations or suspicious patient, further chest X-ray is necessary.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Sep 2019
[Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): quality thresholds for study design and humane modeling endpoints].
Preclinical animal studies are mandatory before new treatments can be tested in clinical trials. However, their use in developing new therapies for sepsis has been controversial because of limitations of the models and inconsistencies with the clinical conditions. In consideration of the revised definition for clinical sepsis and septic shock (Sepsis-3), a Wiggers-Bernard Conference was held in Vienna in May 2017 to propose standardized guidelines on preclinical sepsis modeling. ⋯ Relevant biological variables and comorbidities should be included in the study design and sepsis modeling should be extended to mammalian species other than rodents. In addition, the need for source control (in case of a defined infection focus) should be considered. These recommendations and considerations are proposed as "best practices" for animal models of sepsis that should be implemented.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Aug 2019
Meta Analysis[Early white blood cell count in predicting mortality after acute paraquat poisoning: a Meta-analysis].
To evaluate the prognostic value of early white blood cell count (WBC) in patient of acute paraquat poisoning. ⋯ The early WBC has a certain predictive value for the prognosis of acute paraquat poisoning patients.