Folia medica Cracoviensia
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Folia medica Cracoviensia · Jan 2011
ReviewPathophysiology advances in the treatment of pulmonary hypertension.
The pulmonary hypertension (PH) is the disease with still not clear pathophysiology. The possibilities of current pharmacological treatment of this disorder are unfortunately relatively small, thus the advances in searching of new agents effective in this disease are in progress. The article briefly discusses the present PH classification, its basic etiopathogenesis description and the current and potential possibilities of the pharmacological intervention.
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Folia medica Cracoviensia · Jan 2011
Increased c-Fos expression in nodose ganglion in rats with electrical vagus nerve stimulation.
Central nervous system receives information from the gut and modifies food intake mainly by vagus nerves. Some our data show that long-term electrical vagus nerve stimulation (VNS), which "mimics" satiety signal from gut, may cause reduction of body mass and decrease in food intake. ⋯ Increase in c-Fos expression in left nodose ganglion neurons confirms the afferent transmission of the signal (generated by MS) from periphery to the brain by the vagal nerves.