Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · Apr 2006
[Septic shock in patients with blood diseases. Analysis of clinical situation, treatment and outcome in sixty patients].
Septic shock is one of the major direct causes of death in patients in hematology departments. The aim of the study was to identify situations and factors associated with septic shock in patients with blood diseases. We analyzed the medical treatment of septic shock and its outcome, we based on data from clinical history. ⋯ The most important factors influencing survival in septic shock is patient's organ sufficiency and adequacy of applied antibiotics (early goal-directed antibiotic therapy)--in the same way the sensitivity of microorganisms to this treatment. The neutropenia didn't influence an outcome. The best results were achieved in patients whom combinations of three antibiotics were given: beta-lactam + aminoglicoside + glicopeptide antibiotic or carbapenem + glicopeptide antibiotic + fluorochinolon.