Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · Oct 2009
Glycemic profile and effectiveness and safety of insulin therapy in septic patients: is the blood glucose level sufficient?
Hyperglycemia in sepsis is managed by intensive insulin therapy, which can cause hypoglycemia. ⋯ Patients who died experienced more episodes of hyperglycemia, spontaneous hypoglycemia and greater variation in the daily glycemia level. Daily glycemia variation is more reliable than a mean glycemic level in evaluating glucose homeostasis in septic patients. Few episodes of severe insulin-induced hypoglycemia occurred while using the nurse-controlled insulin therapy protocol.