Polskie Archiwum Medycyny Wewnętrznej
-
Pol. Arch. Med. Wewn. · Jun 2020
The impact of cytogenetic evolution and acquisition of del(17p) on the prognosis of multiple myeloma patients.
Prognosis of patients with newly diagnosed multiple myeloma (MM), a third most common hematological cancer, is dependent on baseline cytogenetics. However, little is known about the prognostic significance of cytogenetic evolution (CE) at the time between the diagnosis and relapse of MM. ⋯ Presence of CE and, particularly, the acquisition of new del(17p) at relapse, negatively affect the outcome of MM. Therefore, re‑evaluation of FISH at MM relapse should be included in routine clinical practice.
-
Pol. Arch. Med. Wewn. · Jun 2020
Diagnostic role of chest computed tomography in coronavirus disease 2019.
Coronavirus disease 2019 (COVID‑19) is an infectious disease caused by a novel strain of coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), that appeared in China in December 2019 and spread globally, evolving into the currently observed pandemic. The laboratory diagnosis of SARS‑CoV‑2 infection is currently based on real‑time reverse transcriptase-polymerase chain reaction (RT‑PCR) testing, and imaging cannot replace genetic testing in patients with suspected COVID‑19. ⋯ In these settings, a rapid presumptive diagnosis of COVID‑19 potentially offered by CT might be an advantage, in addition to obvious benefits of delineating the nature and extent of pulmonary lesions. In the present paper, we reviewed the diagnostic role of chest CT in patients with COVID‑19.
-
Pol. Arch. Med. Wewn. · Jun 2020
The clinical value of routine analysis of cardiac implantable electronic devices after death in the tertiary cardiovascular centre.
The postmortem interrogation of cardiac implantable electronic devices (CIEDs) has not been regularly practiced yet. We presumed that it can provide data not only on the mechanism of the patient's death but also on possible device malfunctions contributing to its occurrence. ⋯ To our knowledge, this is the first study to date to combine the clinical follow‑up of patients before death and on admission at the end of life, autopsy results, and postmortem CIED interrogation. Having implemented the device interrogation, we found 6 CIED‑related events potentially associated with patients' death, which were not detected before its occurrence.
-
Pol. Arch. Med. Wewn. · Jun 2020
Gender differences in the frequency of gastrointestinal symptoms and olfactory or taste disorders among 1,942 non-hospitalized patients with COVID-19.
The coronavirus disease 2019 (COVID 19) is a communicable disease caused by a novel coronavirus. ⋯ This study demonstrated that olfactory and taste disorders are frequent symptoms in patients with mild‑to‑moderate COVID‑19. Moreover, our study indicated sex differences in the frequency of gastrointestinal symptoms and olfactory or taste disorders among nonhospitalized patients with COVID‑19.