Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · Nov 2022
Clinical insights into the role of immunosuppression and its disturbances in solid organ transplant recipients with coronavirus disease 2019.
The COVID-19 pandemic has disproportionately affected patients who have undergone solid organ transplantation (SOT). ⋯ In our study, kidney transplant recipients showed significant disturbances of tacrolimus metabolism, which may account for kidney function worsening during COVID‑19. Moreover, infection was more common in patients with recent kidney or heart transplant, which suggests that the level of immunosuppression may affect morbidity related to SARS‑CoV‑2 infection.
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Pol. Arch. Med. Wewn. · Nov 2022
The cardiometabolic predictive value of anthropometric parameters, vascular ultrasound indexes and fat depots among patients with high cardiovascular risk: an 8-year prospective cohort study.
Adiposity has a few phenotypes associated with various levels of risk for diabetes mellitus (DM), but their exact predictive value is not well understood. ⋯ A complex assessment of the adipose tissue in patients with CCS is a valuable method for improving metabolic risk stratification. Some anthropometric and ultrasound parameters, such as PreFT or body surface area, were associated with IR and DM development.
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Pol. Arch. Med. Wewn. · Nov 2022
ReviewChallenges in pulmonary rehabilitation: COVID-19 and beyond.
Pulmonary rehabilitation is a comprehensive multidisciplinary intervention requiring a team involving an expert chest physician, an exercise training specialist, a nutritional expert, a psychologist, a social worker, and an occupational therapist, who together aim at improving respiratory functional capacity in patients with chronic obstructive pulmonary disease (COPD). We aimed at evaluating the effectiveness of pulmonary rehabilitation in a large number of trials, systematic reviews, and meta‑analyses in pre-COVID-19 conditions, and the impact of pulmonary rehabilitation during the COVID‑19 pandemic was estimated based on results of abundant available studies. ⋯ The response to rehabilitation in patients with COVID‑19 is also satisfactory. The effectiveness of pulmonary rehabilitation in COPD patients shows an evolving need for health care professionals to design an individually tailored pulmonary rehabilitation program for patients with COVID-19 to alleviate the chronic symptoms and reduce complications.
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Pol. Arch. Med. Wewn. · Nov 2022
Irritable bowel syndrome following COVID-19: underestimated consequence of infection with SARS-CoV-2.
Gastrointestinal (GI) symptoms are a common manifestation of COVID‑19. ⋯ Persistent GI symptoms following COVID‑19 are frequent and deserve significant and growing attention of gastroenterologists and other health care practitioners. The Rome IV criteria may be too strict to address the full spectrum of GI symptoms following COVID‑19.