Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · Dec 2022
Meta AnalysisAssociation between inherited thrombophilia and venous thromboembolism in patients with Non-O Blood Type: a meta-analysis.
Hereditary conditions, including non‑O blood group or thrombophilic alterations such as factor V Leiden (FVL) and G20210A prothrombin mutation (G20210A PTM), are usually considered risk factors for venous thromboembolism (VTE). ⋯ The co‑occurrence of FVL and the non‑O group enhances the risk of VTE that could have clinical influence and drive therapeutic corrections. The coexistence of PTM and the non‑O blood group seems to play a less important role in the incidence of VTE.
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Pol. Arch. Med. Wewn. · Dec 2022
Prevalence, predisposing factors and strategies to reduce polypharmacy among older patients in Poland.
The world's elderly population is growing dramatically. Pharmacotherapy in seniors is particularly challenging due to changes in metabolism, multimorbidity, and a great interest in nonprescription drugs. ⋯ The high prevalence of polypharmacy resulting from multimorbidity confirms the need for the implementation of combined medical and pharmaceutical care of the geriatric patients.
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Pol. Arch. Med. Wewn. · Dec 2022
The associations between vitamin D, bone mineral density and the course of inflammatory bowel disease in Polish patients.
There are various factors contributing to the pathogenesis of osteoporosis in inflammatory bowel disease (IBD), including steroid therapy, malnutrition, and vitamin D deficiency. ⋯ Vitamin D may not be the only factor affecting BMD. Patients with IBD should supplement a higher dose of vitamin D than healthy adults.
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Pol. Arch. Med. Wewn. · Dec 2022
Atherosclerotic renovascular disease and cardiovascular risk: new concepts.
Renal vascular hypertension (RVHT) is one of the most common secondary forms of hypertension. It is estimated that 1% to 5% of all cases of hypertension can be attributed to RVHT. RVHT is generally caused by progressive stenosis of the renal artery most often due to atherosclerosis, and less often caused by fibromuscular dysplasia. ⋯ Atherosclerotic renovascular disease is recognized as a relevant risk factor for cardiovascular morbidity and mortality. Studies published so far documented ARAS as a predictor of higher cardiovascular risk and showed that mortality after incidental ARAS diagnosis is much higher than that observed in the general population. Proper recognition of the patients with ARAS who would benefit from interventional treatment is crucial, particularly for identification of patients with true resistant hypertension, flash pulmonary edema, and progressive impairment of renal function.