Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · Feb 2023
A deep learning model to identify fluid overload status in critically ill patients based on chest X-ray images.
Recent studies have highlighted adverse outcomes of fluid overload in critically ill patients. Therefore, its early recognition is essential for the management of these patients. ⋯ As CXR is routinely used in the intensive care unit, a simple, fast, low‑cost, and noninvasive DL model based on this modality can be regarded as an effective supplementary tool for identifying fluid overload, and should be widely adopted in the clinical setting, especially when invasive hemodynamic monitoring is not available.
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Pol. Arch. Med. Wewn. · Feb 2023
Genetic data protection as an indispensable element of genomic medicine development.
The immense progress in molecular biology observed in the last decades has led to a fundamental change in our understanding of the etiology of human diseases. Whole genome analyses, both DNA sequencing and microarray comparative genomic hybridization, allowed for identification of previously unknown diseases and syndromes. Therefore, in difficult‑to‑diagnose cases, clinical diagnosis is being replaced by molecular diagnosis (molecular dysmorphology, genomic medicine). ⋯ The respective legal acts and protective measures should take into account several different aspects. The present paper explores major benefits and risks associated with international sharing of vast databases of genetic material, and presents legal provisions applied in the European Union, the United States, and China. The latter part is based on the respective acts themselves, as well as on analyses and commentaries by other scholars.