Polskie Archiwum Medycyny Wewnętrznej
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Pol. Arch. Med. Wewn. · May 2023
Differences between the course of SARS-CoV-2 infections in the periods of the Delta and Omicron variants dominance in Poland.
Up to now, COVID‑19 caused more than 6 million deaths worldwide. So far, 5 variants of concerns have been identified, with Delta and Omicron being the subject of our analysis. ⋯ The Delta variant is associated with a more severe clinical course of the disease and a higher risk of death than the Omicron variant.
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Pol. Arch. Med. Wewn. · May 2023
ReviewHow to predict recurrent venous thromboembolism and bleeding? A review of recent advances and their implications.
After the first venous thromboembolism (VTE), anticoagulant treatment duration should be based on the balance between the risk of recurrence and bleeding. However, this decision is challenging on the individual level. Prediction models that accurately estimate these risks may help selecting patients that would benefit from either short or indefinite anticoagulant treatment. ⋯ Notably, these models are rarely used in clinical practice and none of them is incorporated in current guidelines due to insufficient accuracy or insufficient validation. Moreover, evidence supporting the value of implementing these models is still lacking. Before these models can be used in routine care, further refinement may be required, and their added value and feasibility should be proven in both management and implementation studies.