Zhonghua yi xue za zhi
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Zhonghua yi xue za zhi · Feb 2012
[Changes of glycogen synthase kinase-3β and its phosphorylation in spinal cord neurons in rats with incisional pain-remifentanil-induced hyperalgesia].
To investigate the change in glycogen synthase kinase-3β (GSK-3β) in spinal cord neurons in rats with incisional pain (IP)-remifentanil-induced hyperalgesia. ⋯ These data indicate that the increased GSK-3β activity in rats spinal cord neurons is involved in remifentanil-induced hyperalgesia.
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Zhonghua yi xue za zhi · Feb 2012
[Clonidine and dexmedetomidine's effect on the altered expressions of growth associated protein-43 mRNA in rat dorsal root ganglion during the development of chronic neuropathic pain].
To explore the effects of α(2) adrenergic receptor (α(2)AR) agonists clonidine and dexmedetomidine on the injury model of peripheral nerve chronic constriction in rats. ⋯ Clonidine and dexmedetomidine both show evident analgesic effects on chronic neuropathic pain in rats probably through a reduction of nerve regeneration. But dexmedetomidine has a better efficacy due to of its high selectivity of α(2)AR.
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Zhonghua yi xue za zhi · Feb 2012
[Cement leakages in percutaneous vertebroplasty:analysis of postoperative computed tomography].
To evaluate the influencing factors of cement leakage in vertebroplasty for the treatment of osteoporosis vertebral compression fracture (OVCF) and vertebral metastases (VM). ⋯ As a common occurrence in vertebroplasty, cement extravasation is well-tolerated in most patients. It occurs more frequently in the patients with VM than those with OVCF, especially in cases of leakage into paravertebral vein. Cement leakage into disc or paravertebral soft tissue is predisposed in vertebrae with end plate, cortical defects or osteolysis.
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Zhonghua yi xue za zhi · Feb 2012
[Risk factors for excessive bleeding in patients undergoing open heart surgery with cardiopulmonary bypass].
To evaluate the pre- and intraoperative risk factors associated with excessive bleeding during the perioperative period in adult patients undergoing open heart surgery with cardiopulmonary bypass (CPB). ⋯ Age ≥ 65 years, previous sternotomy, preoperative low hematocrit concentration, CPB duration ≥ 120 min and complex operation were the significant predictors for excessive bleeding in patient undergoing open heart surgery with CPB.
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Zhonghua yi xue za zhi · Jan 2012
[Predictors and reasons for readmission into cardiac intensive care unit].
To evaluate the predictors and reasons for readmission into cardiac intensive care unit (ICU). ⋯ NYHA classification and the length of first ICU stay are independent risk factors of readmission. Respiratory complications are the most common reasons for readmission.