Zhonghua yi xue za zhi
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Zhonghua yi xue za zhi · Feb 2005
[Detection of integration status of human papillomavirus 16 in cervical precancerous lesions].
To investigate the prevalence of integration of human papillomavirus 16 (HPV16) DNA into the host genome in cervical squamous intraepithelial lesions (SIL). ⋯ HPV16 integration into the host genome is already present in some of CIN lesions. The multiplex PCR estimation of the HPV L1, HPV16 E2, E6 genes and E2/E6 ratio could be a simple method for detecting HPV/HPV16 infection and its integration status in liquid-based residual samples. It would be a helpful complementary tool for cytological screening to identify those patients at high risk of developing high-grade squamous intraepithelial lesions and cervical cancer.
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Zhonghua yi xue za zhi · Jan 2005
Multicenter Study[Two year follow-up of acute ischemic syndrome without ST elevation].
To analyze the characteristics, treatment, and natural course during two years of the patients with acute coronary ischemic syndrome (ACS) without ST elevation in China as a part of the international multicentre registry of acute ischemic syndrome, Organization to Assess Strategies for Ischemic Syndromes (OASIS). ⋯ Most patients with acute ischemic syndrome without ST elevation in China are diagnosed as unstable angina. The patients with acute ischemic syndrome are diagnosed as unstable angina mostly in China. More than half of the patients are treated with anti-platelets, nitrates, beta-blockers, calcium antagonists, and ACEI during hospitalization. The medication rate gradually decreases after discharge. The two-year mortality is 8.0%. The most common causes of death include severe arrhythmias and sudden death.
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Zhonghua yi xue za zhi · Jan 2005
Randomized Controlled Trial Multicenter Study Clinical Trial[Curative effect of gabapentin on refractory epilepsy].
To assess the safety and efficacy of gabapentin in treatment of refractory epilepsy. ⋯ Gabapentin at a dosage of 1200 mg/d is safe and effective in treatment of epilepsy.