Przegla̧d lekarski
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Surgical treatment for Rathke cleft cysts--Intrasellar and suprasellar cysts are often lesions observed in the neuroradiological examinations. The majority of them (craniopharyngioma, cystic pituitary adenoma) are histologically neoplasmic. The others originate from the remnants of the embryonic diverticulum which arise from the roof of the stomodeum. ⋯ Histological examination confirmed Rathke cleft cyst. There were no serious complications in our group. Follow-up examination comprises periodic endocrinological and radiological investigations.
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The aim of this study was to determine relations between the clinical state and the severity of liver damage comparing to the amount of ingested paracetamol, time since ingestion and serum concentration of paracetamol with patients after acute intoxication with this drug. A retrospective analysis of medical records of 95 patients hospitalized in the Toxicology Department in Kraków or treated in the Toxicological Admission Room in 2002-2004 years because of acute paracetamol intoxication was performed. The general clinical state connected with intoxication and the severity of liver damage were determined using the Poisoning Severity Score (PSS). ⋯ A positive correlation between time since ingestion of paracetamol to hospitalization and the gravity of poisoning according to PSS scale was also statistically significant. A paracetamol concentration measured during admission to the hospital had no influence on neither the clinical state of patient nor the severity of liver damage. We conclude that the therapeutical approach should consider possibly shortening of the time since drug ingestion to hospitalization and institution of specific treatment (N-acetylcysteine) as well as minimalization of the paracetamol dose, which could be absorbed, by different methods of elimination from the GI tract (eg., gastric lavage, activated charcoal laxatives).
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Endogenous evoked potentials (P300) are elicited by several stimuli, and are electrophysiological consequence of cognitive processing. Abnormalities have often been reported in dementive syndromes, demyelinating diseases, metabolic disorders, CNS tumors, phacomatoses, neuroinfections, attention deficit hyperactivity disorder and epilepsy. The role of this element of neurophysiological characteristics is debated in migraine, pato-genetically undefined, and other primary headaches. ⋯ The findings of shortened latency of P300 potentials in children with migraine, esp. migraine with aura may contribute to migraine pathogenesis. There were no significant differences in the latency and amplitude of P300 potentials in children with migraine without aura compared with the frequent ETTH. This finding does not add further information to the differentiation of both types of primary headaches.
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The case of a 58-year old patient, who nearly experienced cardiac arrest due to growing oxygen deficiency, was presented. The arrest was brought about by the impossibility to perform endotracheal intubation. A laryngeal mask successfully replaced an intubation tube and enabled artificial lung ventilation and restoration of correct blood oxygenation.
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Contemporary treatment of cancer (intensive chemotherapy, radiotherapy, radical surgery, stem cell transplantation) and severe non-neoplastic blood diseases resulted in significant improvement of treatment results. Currently over 70% of children with cancer can be cured. However, at the same time number of severe complications, including life-threatening infections began to increase. ⋯ Our presentation will review currently available antifungal drugs and guidelines for treatment of specific fungal infections. The plan of antifungal treatment must include not only the species of fungal pathogen, but also the site and extent of infection, as well as patient status, including stage of primary disease, previous therapy and previous organ damage. Rational management would allow to choose appropriate antifungal drug, optimize dosage and duration of treatment and estimated costs, and above all to improve the chance to effectively control the life-threatening fungal infections.