Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
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Zhonghua Jie He He Hu Xi Za Zhi · Feb 1989
Comparative Study[Airway responsiveness to isocapnic hyperventilation with room temperature air].
Isocapnic hyperventilation (IHV) with room temperature dry gas was evaluated in 63 asthmatics and 33 normal subjects, in order to asses the clinical relevance of the technique as a simplified test of airways hyperreactivity. The results between IHV and methacholine challenge (MCH) were compared in 32 asthmatics. Mostly asthmatics revealed obvious bronchoconstriction and average 21.4 +/- 14.8% decrease in FEV1 (delta FEV1) after hyperventilation. ⋯ Three of the asthmatics demonstrated bronchodilative reaction and FEV1 increased notably than the base after hyperventilation. The positive percentages of IHV and MCH were similar (P greater than 0.05). The results suggest the IHV with room air determine bronchial reactivity is a simple and secure method.