Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
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Zhonghua Jie He He Hu Xi Za Zhi · Jun 2004
Comparative Study[Comparative analysis of respiratory bronchiolitis-associated interstitial lung disease and desquamative interstitial pneumonia].
To investigate the clinicopathologic characteristics of respiratory bronchiolitis-associated interstitial lung disease (RBILD) and its relationship to desquamative interstitial pneumonia (DIP). ⋯ RBILD could be confused with DIP in clinical manifestations, but can be separated by open lung biopsy. Considering their similarities, these two lesions may be regarded as a same disease entity.
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Zhonghua Jie He He Hu Xi Za Zhi · Jun 2004
[Imbalanced T cell-specific transcription factors T-bet and GATA-3 contributes to type 2 T helper cell polarization in asthmatic patients].
To identify the T helper cell predominant differentiation in asthmatic patients and to explore the modulation of T cell-specific transcription factors T-bet/GATA-3. ⋯ In asthma there is a tendency of Th2 polarization with over-production of Th2-like cytokines in which T-bet deficiency may be a key factor. T-bet might direct T cells to Th1 differentiation while GATA-3 orientated Th2 maturation. Considering the fact that committed Th2 cells underwent re-differentiation induced by T-bet, this novel Th1-specific transcription factor is a fascinating target gene for modifying to restore the Th1 and Th2 balance.