Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
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Zhonghua Jie He He Hu Xi Za Zhi · Jan 2006
Randomized Controlled Trial Multicenter Study[Application of pulmonary infection control window as switching point for sequential invasive to noninvasive ventilation in treatment of severe respiratory failure of chronic obstructive pulmonary disease: a randomized controlled study].
To evaluate the feasibility and the efficacy of early extubation and sequential noninvasive mechanical ventilation (MV) switched by pulmonary infection control window (PIC window) in chronic obstructive pulmonary disease (COPD) with exacerbated hypercapnic respiratory failure. ⋯ Early extubation followed by non-invasive MV initiated at the point of PIC window may decrease the duration of invasive MV and improve the prognosis.
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Zhonghua Jie He He Hu Xi Za Zhi · Jan 2006
Randomized Controlled Trial[The effect of subglottic secretion drainage on prevention of ventilator-associated lower airway infection].
To assess the influence of subglottic secretion drainage (SSD) on the morbidity of ventilator-associated pneumonia (VAP) in mechanically ventilated patients. ⋯ (1) SSD reduced the incidence of VAAI and VAP in patients with MV < 5 d. The onset of VAAI and VAP was delayed in group A as compared with group B. The concentration of bacteria in the subglottic secretion was significantly reduced by subglottic secretion drainage. (2) Migration of the dominant bacteria of the subglottic secretion was one of the important factors for VALAI. (3) The dominant cultured bacteria in the lower airway secretion were gram-negative bacilli, most commonly Pseudomonas aeruginosa and Acinetobacter baumanii.