Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
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Zhonghua Jie He He Hu Xi Za Zhi · Dec 2016
[The diagnostic performance of galactomannan detection for invasive pulmonary aspergillosis in non-neutropenic hosts].
Objective: To evaluate the diagnostic performance of galactomannan(GM)detection in serum and BALF for invasive pulmonary aspergillosis (IPA) in non-neutropenic hosts. Methods: A pospective study was performed for 1 356 non-neutropenic hosts admitted to the Department of Pulmonary and Critical Care Medicine of the First Affiliated Hospital of Wenzhou Medical University from September 2014 to October 2015. Serum GM test was performed for all, and BALF GM test for a proportion of the patients. ⋯ Conclusions: The sensitivity of serum GM test in non-neutropenic hosts was low, but it had a high negative predictive value. The best BALF GM cut-off value was 1.0. The combined serum and BALF GM tests improved the diagnostic performance.