Clinical otolaryngology and allied sciences
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Clin Otolaryngol Allied Sci · Dec 1991
Randomized Controlled Trial Clinical TrialAnalgesia in tonsillectomy: a double-blind study on pre and post-operative treatment with diclofenac.
The efficacy and tolerability of diclofenac suppositories given pre and/or post-operatively were investigated in a randomized double-blind study on 99 patients undergoing tonsillectomy. In one group, 50 mg diclofenac was given 1 h preoperatively, followed by 50 mg directly after the operation. ⋯ The tolerance was good and no serious bleeding complications occurred in either group. In the treatment of post-operative pain after tonsillectomy, the combination of pre and post-operative administration of diclofenac suppositories resulted in significantly lower consumption of rescue analgesics and is thus preferable to administration solely post-operatively.