Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
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Zhongguo Yi Xue Ke Xue Yuan Xue Bao · Feb 2003
[The method of accelerating osteanagenesis and revascularization of tissue engineered bone in big animal in vivo].
To study whether tissue engineered bone can repair the large segment bone defect of large animal or not. To observe what character the fascia flap played during the osteanagenesis and revascularization process of tissue engineered bone. ⋯ The model of 2 cm caprine tibia diaphyseal defect cannot be repaired by goat itself and can satisfy the tissue engineering's demands. Tissue engineered bone had good ability to repair large segment tibia defect of goat. Fascia flap can accelerate the revascularization process of tissue engineered bone. And by this way, it augment the ability of tissue engineered bone to repair the large bone defect of goat.
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Evidence-based medicine combines the patient's preferences with clinical experience and the best research evidence. Randomized clinical trials are considered the most valid research design for evaluating health-care interventions. However, empirical research shows that intervention effects may be significantly overestimated (in one study on average by about 50 per cent) in randomized clinical trials with inadequate methods for generation of allocation sequence, allocation concealment, and double blinding. ⋯ Accordingly, there is an urgent need to improve this situation. Guidelines for Good Clinical (Research) Practice, conduct of more trials as multicentre trials, The Consort Statement, and The Cochrane Collaboration may all help in the application of the best research evidence in clinical practice. By investments in education, applied research, and The Cochrane Collaboration, evidence-based medicine may form a stronger basis for clinical practice.
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Zhongguo Yi Xue Ke Xue Yuan Xue Bao · Dec 2002
Meta Analysis[An appraisal of immunonutrition for clinical nutritional support with a systematic review of English and Chinese documents].
To evaluate the efficacy, safty and economical values of immunonutrition for clinical nutritional support. ⋯ Immunonutrition is associated with decreasing of infectious rates, length of hospitalization and cost in selective operation patients. But current evidence can't affirm the role of immunonutrition on critical illness patients. Further studies are urgently needed to clarify the reliability of immunonutrition in this group.
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Zhongguo Yi Xue Ke Xue Yuan Xue Bao · Aug 2002
Randomized Controlled Trial Comparative Study Clinical Trial[Comparative study of pulmonary function after conventional ultrafiltration or modified ultrafiltration during cardiac surgery of infants].
To compare the effects of conventional ultrafiltration and modified ultrafiltration in protecting patients' pulmonary function during cardiopulmonary bypass. ⋯ The modified ultrafiltration can effectively improve pulmonary function after operations for low weight infants.
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Zhongguo Yi Xue Ke Xue Yuan Xue Bao · Dec 2001
[Application of diapason instrumentation for treatment of unstable lumbosacral spinal stenosis].
To observe the preliminary clinical outcome of using a new instrumentation Diapason system and to introduce the characterization and surgical technique of this new system for treatment of unstable lumbar spinal stenosis. ⋯ Our short-term follow-up and limited cases study showed satisfactory preliminary result of treating unstable lumbar spinal stenosis with Diapason internal fixation.