Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
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This article presents the results of a study on 20 children diagnosed with acute renal failure and treated with renal substitution methods at the Iasi IVth Clinic of Pediatric Nephrology in the interval 2003-2008. Treatment by intermittent hemodialysis IHD), peritoneal dialysis (DP), and continuous replacement--hemofiltering (HF) depends on the patient's features and unit resources. The advantages and limitations of every method of treatment are discussed. Future therapies for acute renal failure may find strategies for eliminating the inflammatory response.
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Inflammation is a fundamental biologic process evolutionally preserved by a germ line code. The interplay of the epigenetic with the environment directs the code to temporally distinct inflammatory responses, which can be acute or chronic. The aim of this study is to present new aspects regarding the resolution of inflammation. ⋯ Granulocytes promote the switch of arachidonic acid-derived prostaglandins and leukotrienes to lipoxins, active antiinflammatory and pro-resolution mediators. The apoptosis of the neutrophils coincides with the biosynthesis of resolvins and protectins from omega-3 polyunsaturated fatty acids and releases anti-inflammatory and reparative cytokines. This information could lead to new treatments for inflammatory diseases.
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Rev Med Chir Soc Med Nat Iasi · Apr 2011
[Sensitization to ascaris lumbricoides and asthma severity in children].
There is little information concerning asthma severity and sensitization to Ascaris lumbricoides in pediatric patients. ⋯ Sensitization to Ascaris lumbricoides is associated with increased severity of asthma among Romanian children. This association is mediated by a high degree of atopy among the asthma children sensitized to Ascaris lumbricoides and belonging to a population with a low prevalence of helminthiasis.
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Rev Med Chir Soc Med Nat Iasi · Apr 2011
[Upper-extremity deep vein thrombosis: current concepts in diagnosis and treatment].
Upper-extremity deep vein thrombosis is a rare manifestation of venous thromboembolic disease. In the past few decades, the clinical importance of upper-extremity deep vein thrombosis has increased because of the wider use of central venous catheters and the development of ultrasonography as a simple and accurate objective diagnostic method. Primary upper-extremity deep vein thrombosis is a rare disorder (2 per 100,000 persons per year), which comprises (1) Paget-Schroetter Syndrome, also known as effort thrombosis, and (2) idiopathic upper-extremity deep vein thrombosis. ⋯ Contrast venogram is the standard diagnostic test for characterization of the anatomy. A staged, multimodal approach to Paget-Schroetter Syndrome can effectively restore venous patency, reduce the risk of rethrombosis, and return the patient to normal function. Primary care physicians should be aware of this condition and its atypical presentations, because delayed recognition in a high-functioning persons can be potentially disabling.