Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Merging PK/PD information in a minimally parameterized model of the neuromuscular blockade.
A recursive system identification algorithm that merges PK/PD information in a minimally parameterized Wiener model for the NMB level is presented. The results show that the coupling between one parameter from the linear block and one from the static nonlinearity is advantageous, when evaluated on a database of 60 real collected NMB cases.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Estimated venous return surface and cardiac output curve precisely predicts new hemodynamics after volume change.
In our extended Guyton's model, the ability of heart to pump blood is characterized by a cardiac output curve and the ability of vasculature to pool blood by a venous return surface. These intersect in a three-dimensional coordinate system at the operating right atrial pressure, left atrial pressure, and cardiac output. ⋯ Using the average values for two logarithmic function parameters, and for two slopes of a surface, we were able to estimate cardiac output curve and venous return surface. The estimated curve and surface predicted new hemodynamics after volume change precisely.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2009
A wavelet based method for steady-state detection in anesthesia.
With the recent concern on patient's outcome following general anesthesia, automatic control of drugs has been a field of interest. The Bispectral Index (BIS) is an EEG based hypnosis monitor, in current use at the operating theatre as a guiding tool for the anesthesiologist to titrate drugs, and prevent awareness. ⋯ A steady-state index was obtained using a wavelet analysis technique for trend detection. This tool may be used in the future to model the drug's combined effect on the hypnosis indices, and also to bring some insight on disturbances not related to drug changes.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2009
Using A-weighting for psychoacoustic active noise control.
Conventional adaptive active noise control (ANC) methods aim to attenuate the acoustic noise over the frequency band of interest indiscriminately using the sound pressure level (SPL) measurement (or the measurement of the residual error variance). However, SPL does not correctly reflect the human perception of attenuated noise due to the frequency selective sensitivity of human hearing system. A-weighting is a commonly used weighting filter for measuring the noise. ⋯ In this paper, we aim to improve the performance of adaptive noise cancellation method from the psychoacoustic point of view by incorporating the A-weighting into the ANC system design. Loudness is used as the psychoacoustic criterion for evaluating the ANC system performance. Simulation results illustrate the effectiveness of the proposed method.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2009
Fuzzy control for closed-loop, patient-specific hypnosis in intraoperative patients: a simulation study.
Research has demonstrated the efficacy of closed-loop control of anesthesia using bispectral index (BIS) as the controlled variable, and the recent development of model-based, patient-adaptive systems has considerably improved anesthetic control. To further explore the use of model-based control in anesthesia, we investigated the application of fuzzy control in the delivery of patient-specific propofol-induced hypnosis. In simulated intraoperative patients, the fuzzy controller demonstrated clinically acceptable performance, suggesting that further study is warranted.