Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
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Conf Proc IEEE Eng Med Biol Soc · Jan 2008
Predict the neurological recovery under hypothermia after cardiac arrest using C0 complexity measure of EEG signals.
Clinical trials have proven the efficacy of therapeutic hypothermia in improving the functional outcome after cardiac arrest (CA) compared with the normothermic controls. Experimental researches also demonstrated quantitative electroencephalogram (qEEG) analysis was associated with the long-term outcome of the therapeutic hypothermia in brain injury. Nevertheless, qEEG has not been able to provide a prediction earlier than 6h after the return of spontaneous circulation (ROSC). ⋯ Significantly greater C0 complexity was found in hypothermic group than that in normothermic group as early as 4h after the ROSC (P0.05). C0 complexity at 4h correlated well with the 72h neurodeficit score (NDS) (Pearson's correlation = 0.882). The results showed that the C0 complexity could be an early predictor of the long-term neurological recovery from cardiac arrest.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2008
A two-stage approach to positioning and identification of tracheal intubation using LED-based lightwand and acoustic models.
This paper proposes a two-stage approach to positioning and identifying tracheal intubations by computer-assisted diagnosis system. First, an innovated LED-based lightwand is developed for positioning the opening of the trachea and inserting the endotracheal tube rapidly. The proposed LED-based lightwand instrument significantly reduces the effects of temperature reaction without changing transillumination through the tissue. ⋯ Several subjective and objective experiments are performed to examine the practicability of the proposed approach and systems. The preliminary results show that the proposed LED-based lightwand instrument outperformed in the tip temperature without the influence on transillumination. The proposed parameters of average vibration parameter variance (AVPV) and frequency-domain energy variance (FEV) revealed the potential for distinguishing between the tracheal and esophageal intubations.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2008
Thermal effect of sonophoresis for accelerating the analgesic effect of local anesthetics on rat tail nerve.
Sonophoresis is an ultrasound transdermal drugs delivery system. The eutectic mixture of local anesthetics (EMLA) has been used clinically for anesthesia but requires at least one hour to take effect and lacks of analgesia's objective assessment. We proposed that sonophoresis could reduce the duration of EMLA analgesia effect onset and be assessed by sensory conduction studies. ⋯ We have objectively examined the sonophoresis effect of ultrasound by investigating the effects of EMLA. Applying ultrasound for 5 min reduces the onset time of EMLA analgesia from 60 min to less than 20 min. Ultrasound sonophoresis of analgesic drugs is potentially useful in the treatment of carpal tunnel syndrome, tooth extraction, and other applications of analgesia.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2008
Comparative StudyPerformance evaluation of three methods for respiratory signal estimation from the electrocardiogram.
A comparative study of three methods for estimating respiratory signal through electrocardiogram (ECG) was carried out. The three methods analyzed were based on R wave area, R peak amplitude and heart rate variability (HRV). For each method, cross-correlation coefficient and spectral coherence in a range of frequencies up to 0.5 Hz were computed between the ECG derived respiratory signals (EDR) and the three real respiratory signals: oronasal, and two inductance plethysmographies recordings (chest and abdominal). Results indicate that EDR methods based on R wave area and HRV are better correlated and show a wider spectral coherence with real respiratory signals than the other EDR method based on R peak amplitude.