Revista médica de Chile
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Creutzfeldt-Jakob disease (CJD) is a prion affection that typically produces a rapidly progressive dementia with different neurologic and extra-neurologic manifestations. ⋯ In this group of patients we observed the heterogeneity of the clinical manifestations of the disease, the frequent imaging and electroencephalographic alterations and the short evolution time leading to death.
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Revista médica de Chile · Aug 2021
Review[Measurement of exhaled nitric oxide fraction in lung diseases].
Exhaled Nitric Oxide fraction measurement is a new method for the evaluation of respiratory diseases. It has good correlation with airway inflammation and decreases with the administration of corticosteroids. ⋯ It can be used routinely to evaluate the response and adherence to treatments. This article reviews the biology of Nitric Oxide, and the measurement, interpretation, and main clinical uses of Exhaled Nitric Oxide Fraction.
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Revista médica de Chile · Aug 2021
Adverse events associated with antimicrobial compounds in a general hospital in Chile.
Antimicrobial compounds are associated with a wide range of adverse events (AE) and some of them can be potentially preventable. ⋯ Antimicrobial AE involved a wide diversity of compounds, occurred in different hospitalization units, affected patients of a wide age range and attacked different systems or organs. An important fraction was potentially avoidable.
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Revista médica de Chile · Aug 2021
[Clinical features of COVID-19 infection among patients consulting at an emergency service].
COVID-19 is a serious public health problem worldwide. ⋯ Clinical features of COVID-19 infection were highly unspecific in these patients. Clinical diagnostic prediction models could be useful to support healthcare decision making at primary care setting.
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Revista médica de Chile · Aug 2021
Case Reports[Intestinal relapse of a cutaneous melanoma. Report of one case].
Digestive tract primary melanoma is uncommon. However, metastatic lesions are more frequent and occur mainly in the small intestine. We report a 69-year-old male patient who consulted for a hyperpigmented skin lesion on the left thigh associated with multiple subcutaneous nodules. ⋯ Laparoscopic resection with primary anastomosis was performed with good clinical evolution. The definitive biopsy showed a melanoma metastasis with two of three lymph nodes positive for metastasis and a non-mutated BRAF gene. In conclusion, a single intestinal recurrence of melanoma is rare and requires an active search, since it can be resected using minimally invasive techniques.