Revista médica de Chile
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Revista médica de Chile · Oct 2022
Review[Biological effects due to exposure to different concentrations of oxygen from hypo to hyperoxemia].
The systemic effects of oxygen deficiency or excess are not thoroughly described. Knowledge is evolving towards the description of beneficial and detrimental effects of both extremes of partial pressure of oxygen (PaO2). The cellular and tissue mediators derived from the modulation of the oxidative tone and the production of reactive oxygen species (ROS) are widely characterized biochemically, but the pathophysiological characterization is lacking. ⋯ On the other hand, the modulation of the hypoxic response associated with exposure to high altitude environments (hypobaric), favors Chile and its highlands as a natural laboratory to determine certain cardiovascular, cerebral and metabolic responses in the resident population. Also, the consequences of the intermittent exposure to high altitudes in workers also deserves attention. This review discusses the physiopathological response to hypo and hyperoxemia, associated with environments with different oxygen concentrations, and brings back the concept of oxygen as a pharmacological mediator in extreme environments such as high altitudes and hyperbaric medicine in divers, decompression sickness, osteonecrosis associated with radiotherapy and sudden sensorineural hearing loss.
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Revista médica de Chile · Oct 2022
[Frequency of burnout syndrome among health care workers during COVID-19 pandemic].
COVID-19 pandemic increased the prevalence of burnout syndrome. ⋯ Healthcare workers showed concerning levels of burnout syndrome. It is recommended to pay special attention to high levels of emotional exhaustion in nursing and night shift staff. Institutions should develop and apply prevention and emotional support strategies in health personnel.
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Revista médica de Chile · Oct 2022
[Psychometric properties of two surveys about beliefs towards vaccines in general and SARS-CoV-2 vaccine].
Negative beliefs about vaccines can threaten herd immunity and pandemic control. Although beliefs about vaccines influence vaccination intention, there are no valid instruments that evaluate this in the Latin American population. ⋯ The scales evaluated here are reliable and valid measures that showed associations with vaccination intention in the Chilean population.
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Revista médica de Chile · Oct 2022
Case Reports[Fecal microbiota transplantation in an older patient with Clostridioides difficile recurrent infection. Report of one case].
Clostridioides difficile infection (CDI) is a major public health problem and responsible for significant morbidity and mortality. Eighty percent of CDIs occur in adults older than 65 years of age due to a decreased gastrointestinal microbial diversity, immunosenescence and frailty. ⋯ We report a 75-year-old male with recurrent CDI, who received a FMT after several unsuccessful antimicrobial treatments. He had a satisfactory evolution after the procedure and remained without diarrhea during the ensuing five months.