Mayo Clinic proceedings
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Mayo Clinic proceedings · Jul 1996
Gonadotroph adenoma of the pituitary gland: a clinicopathologic analysis of 100 cases.
To determine the clinical and pathologic features in a large cohort of randomly selected patients with gonadotroph pituitary adenomas. ⋯ Most patients with clinically evident gonadotroph pituitary tumors have loss of vision and hypopituitarism. Hypersecretion of FSH or LH is unusual, and no distinct hormone-dependent clinical phenotype is present. Transsphenoidal surgical treatment generally yields normalization or improvement of visual field defects.