Mayo Clinic proceedings
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Mayo Clinic proceedings · Mar 2002
Comment Letter Case ReportsHidden danger of generic medications.
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Mayo Clinic proceedings · Mar 2002
Case ReportsReversible myelopathy in a 34-year-old man with vitamin B12 deficiency.
Vitamin B12 deficiency is common, with most patients lacking classic features of advanced severe deficiency. Early diagnosis and treatment prevent severe anemia and irreversible damage to the nervous system. ⋯ Prompt diagnosis based on the measurement of serum methylmalonic acid and treatment with cyanocobalamin injections led to rapid resolution of clinical manifestations and magnetic resonance imaging abnormalities. We review the literature of magnetic resonance imaging in vitamin B12 deficiency myelopathy and discuss the issues relating to diagnosis and early treatment of this potentially reversible condition.