Mayo Clinic proceedings
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Mayo Clinic proceedings · Aug 2021
Multicenter StudyAcute Pulmonary Embolism During Pregnancy and Puerperium: National Trends and In-Hospital Outcomes.
To investigate the trend and outcomes of acute pulmonary embolism (PE) during pregnancy and puerperium using a large national database. ⋯ In this contemporary analysis of pregnancy-related hospitalizations, acute PE was uncommon, but rates have not decreased over the past decade. Acute PE during pregnancy and puerperium was associated with high maternal mortality, and the rates of in-hospital mortality have not improved. Future studies to improve prevention and management of acute PE during pregnancy and puerperium are warranted.
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Mayo Clinic proceedings · Aug 2021
ReviewA Proposed Approach for Conducting Studies That Use Data From Social Media Platforms.
The prominence of social media in contemporary society has extended significantly into the health care arena, where both patients and health care providers have used social media platforms to gather, communicate, learn, and share medical content and personal experience in real time. The medical literature has also seen an exponential increase in the number of studies that use data derived from social media coverage of various medical issues and topics. ⋯ We present 6 overarching steps: focus on framing a question that is appropriate for social media evaluation, identification of social media outlet and selection criteria of content, systematic data extraction, assessment of quality of content and sources of bias, analysis of data, and interpretation of study findings. Each step is illustrated with published examples.
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Mayo Clinic proceedings · Aug 2021
Multicenter Study Observational StudyBarriers to ACEI/ARB Use in Proteinuric Chronic Kidney Disease: An Observational Study.
To assess present angiotensin-converting enzyme inhibitor (ACEI) and angiotensin receptor blocker (ARB) use among patients with proteinuric chronic kidney disease (CKD) and examine barriers limiting this guideline-concordant care. ⋯ Discontinuing, rather than never initiating, ACEI/ARB treatment limits guideline-concordant care in proteinuric CKD. Past AKI, hyperkalemia, advanced CKD, and lack of nephrology care were associated with lower use of ACEIs/ARBs, but these putative barriers may in many instances be inappropriate (AKI and advanced CKD) or modifiable (hyperkalemia and lack of nephrology care).