Mayo Clinic proceedings
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Mayo Clinic proceedings · May 2023
Baclofen and the Risk of Encephalopathy: A Real-World, Active-Comparator Cohort Study.
To quantify the risk of encephalopathy associated with oral baclofen compared with other muscle relaxants-tizanidine or cyclobenzaprine. ⋯ The risk of encephalopathy was greater with baclofen vs tizanidine or cyclobenzaprine use. The elevated risk was apparent as early as 30 days and persisted through the first year of treatment. Our findings from routine care settings may inform shared treatment decisions between patients and prescribers.
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Mayo Clinic proceedings · May 2023
Disruption in Blood Pressure Control With the COVID-19 Pandemic: The PCORnet Blood Pressure Control Laboratory.
To explore trends in blood pressure (BP) control before and during the COVID-19 pandemic. ⋯ BP control decreased substantially during the COVID-19 pandemic, with a corresponding reduction in follow-up health care visits among persons with uncontrolled hypertension. It is unclear whether the observed decline in BP control during the pandemic will contribute to future cardiovascular events.