Mayo Clinic proceedings
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Mayo Clinic proceedings · Dec 2022
ReviewSkin Cancer in Solid Organ Transplant Recipients: A Review for the Nondermatologist.
Solid organ transplant recipients (SOTRs) are at increased risk for the development of skin cancer compared with the general population, which requires consistent monitoring and management from a multidisciplinary team. The aim of this review is to provide a comprehensive overview for nondermatologist clinicians, outlining skin cancer diagnosis, treatment pearls, and skin cancer prevention strategies as they relate to SOTRs. A comprehensive search of the literature was conducted through the MEDLINE database with search terms including organ transplantation, transplant recipient, skin cancer, cutaneous neoplasms, management, and therapies. ⋯ Reduction in immunosuppressive medications and surgical intervention are effective therapeutic approaches, and more novel systemic therapies including G protein-coupled receptor inhibitors and immune checkpoint inhibitors are possible options when traditional treatment approaches are not feasible. Checkpoint inhibitor therapy, however, comes with the risk of allograft rejection. With a growing and aging SOTR population, it is essential that SOTRs have support from dermatologists and nondermatologists alike in skin cancer prevention and treatment.
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Mayo Clinic proceedings · Dec 2022
Potentially Preventable Hospitalizations Among Adults With Pediatric-Onset Disabilities.
To examine the risk of any and specific potentially preventable hospitalizations (PPHs) for adults with cerebral palsy (CP) or spina bifida (SB). We hypothesize that PPH risk is greater among adults with CP/SB compared with the general population. ⋯ Adults with pediatric-onset disabilities are at a greater risk for PPHs. Providing better access to preventive care and health-promoting services, especially for respiratory and urinary outcomes, may reduce PPH risk among this patient population.
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Mayo Clinic proceedings · Dec 2022
Implementation of an All-Day Artificial Intelligence-Based Triage System to Accelerate Door-to-Balloon Times.
To implement an all-day artificial intelligence (AI)-based system to facilitate chest pain triage in the emergency department. ⋯ Implementation of an all-day AI-based triage system significantly reduced the D2B time, with a corresponding increase in the percentage of D2B times less than 90 minutes in the emergency department. This system may help minimize preventable delays in D2B times for patients with STEMI undergoing primary percutaneous coronary intervention.
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Mayo Clinic proceedings · Dec 2022
Urinary Sodium-to-Potassium Ratio and Incident Chronic Kidney Disease: Results From the Korean Genome and Epidemiology Study.
To evaluate the association of sodium-potassium intake balance on kidney function. ⋯ A low urinary Na/K ratio may relate with lower CKD development risk in adults with preserved kidney function.