Curēus
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Review
Bicarbonate Therapy for Critically Ill Patients with Metabolic Acidosis: A Systematic Review.
The management of acid-base disorders always calls for precise diagnosis and treatment of the underlying disease. Sometimes additional means are necessary to combat systemic acidity itself. In this systematic review, we discuss the concept and some specific aspects of bicarbonate therapy for critically ill patients with metabolic acidosis (i.e., patients with blood pH < 7.35). ⋯ Twelve trials and case series were included in the final analysis, from which we assessed population, intervention, comparison, and outcome data. The current literature suggests limited benefit from bicarbonate therapy for patients with severe metabolic acidosis (pH < 7.1 and bicarbonate < 6 mEq/L). However, bicarbonate therapy does yield improvement in survival for patients with accompanying acute kidney injury.
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Radiologic findings in combination with clinical symptoms are critical in the diagnosis and evaluation of the severity of lumbar spinal stenosis (LSS) as well as the need for surgical treatment. Dynamic radiographs, computerized tomography (CT), and magnetic resonance imaging (MRI) each provide different but interrelated pieces of information in the patient with lumbar spinal stenosis. Making a treatment decision based only on one of the radiographic studies may negatively affect the treatment outcome. ⋯ With the development of less invasive procedures, lumbar spinal stenosis is being evaluated and treated not only by spine surgeons but also by interventional pain and neuroradiology physicians that may not be totally familiar with the complexity of the pathology and neuro-radiology of LSS. Each radiologic study provides different information. The goal of this report is to provide a framework for the use of studies such as plain X-rays, dynamic films, MRI, and CT scans as well as the importance of different views, and how to use them in evaluating the abnormal radiologic anatomy seen with LSS and in selecting the most appropriate procedure.
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Background Point-of-care ultrasound (POCUS) has many applications in emergency medicine, which have been proven to improve patient outcomes. Training programs and well-established guidelines for its use are available, but Canadian adoption rates and attitudes toward this technology have not been recently assessed. Objectives This study aimed to provide a national assessment of the current use of POCUS in Canadian emergency departments (ED) including patterns of use, attitudes towards its role, descriptors of training experience, as well as barriers to increased utilization. ⋯ Most physicians have formal POCUS training in core applications, and approximately one third have advanced training. Conclusions POCUS training and utilization appear to have increased since the last national assessment. This provides a foundation for future POCUS research.
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Epidural steroid injections (ESIs) are one of the few modalities currently in use for treating chronic spinal pain. There are two approaches: interlaminar ESIs and transforaminal ESIs. Complications arising from either approach are rare, but one such complication is cerebrospinal fluid (CSF) leak leading to intracranial hypotension. ⋯ Further studies are needed involving clotting factors comparing arterial and venous blood. It is also puzzling why the epidural blood from the hematoma did not clot the leak. This concomitancy deserves further attention and may lead to changes in how we manage cervical epidural injection patients who are found to have CSF leak and a spinal epidural hematoma.
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Background The early detection of elevated intracranial pressure (ICP) can not only prevent mortality but also aid in more aggressive management. Brain computed tomography (CT) is a mainstay modality in detecting elevated ICP, but the feasibility of using brain CTs to detect elevated ICP in critically ill patients is limited, especially for patients who require high levels of inotropic support. The optic nerve sheath is a direct extension of the brain meninges. ⋯ The positive predictive value was 92.08% (95% CI, 86.28% to 98.96%), and the negative predictive value was 94.23% (95% CI, 84.47% to 98.00%). Conclusion The greatest accuracy in ONSD was found with a cut-off of >0.58 cm in patients with positive CT brain findings. Therefore, US can be used as an initial screening test when physicians suspect a patient has elevated ICP.