Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
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Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi · Mar 2013
[Mechanism of hematopoietic stem/progenitor cell aging induced by radiation damage].
To explore the mechanism underlying the aging of hematopoietic stem/progenitor cells (HSC/HPC) induced by radiation stress. ⋯ DNA damage and senescence-associated biological changes of Sca-1(+);HSC/HPC can be achieved by X-ray radiation, which may be involved in p16(INK4a);-Rb and p19(Arf);-p53-p21(Cip1/Waf1); signal pathways.