Mymensingh medical journal : MMJ
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Comparative Study
Comparative study between rectally administered misoprostol as a prophylaxis versus conventional intramuscular oxytocin in post partum hemorrhage.
Post partum hemorrhage is a major cause of maternal death in developing country. A prospective, Observational comparative study was carried out in the department of Obstetrics and Gynaecology of Dhaka Medical College Hospital during the period from July 2003 to December 2003 to compare the effectiveness of rectally administered misoprostol with intramuscular oxytocin in prevention of post partum hemorrhage. A total number of 200 women were studied among whom 100 women were received 10 units of oxytocin intramuscularly & 100 women were given 600 microgram misoprostol per rectally. ⋯ No patient had blood loss more than 1000ml and none required blood transfusion in either group. The main side effects of misoprostol were shivering and rise of temperature. So it can be suggested that per rectally administered misoprostol may be effective in the prevention of PPH as an alternative to conventional intramuscular oxytocin.
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It is a cross sectional observational study. Place of study was the ICU of Square Hospitals Ltd. and ICU of Bangabandhu Sheikh Mujib Medical University (BSMMU). All patients who were diagnosed as a case of Ventilator Associated Pneumonia (VAP) in ICU during the one year study period (01.01.2006 to 31.12.2006) were included in this study. ⋯ Other organisms were Staphylococcus aureas, Klebsiella pneumonae, Enterobacter species, Proteus, Candida, Escherichia coli and Methicillin Resistant Staphylococcus aureas. Primary diagnosis of most of the patients was neurosurgical, medical and surgical origin. Mortality was 25.6% in our series.
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Helicobacter pylori (H. pylori) infection is a common and significant public health problem. About 70-90% of the population in developing countries and 25-50% in developed countries were infected with H. pylori. Many studies have been undertaken concerning the role of H. pylori in the etiopathogenesis of chronic gastritis and peptic ulcer, as well as its role in the development of stomach malignancies. ⋯ It was also concluded from the study that severity of gastritis associated with H. Pylori increases with the heavy load of infection. To confirm the association prospective study with large sample size is recommended.
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Randomized Controlled Trial Comparative Study
Comparative study of stress response to central venous cannulation under local anesthesia and general anesthesia in patients undergoing open heart surgery.
The open heart surgery like coronary artery bypass graft (CABG), repair of ventricular septal defect (VSD) and atrial septal defect (ASD), valve replacement need a circulatory arrest, which is normally safe under conventional hypothermia. During this time not only the heart and lungs are bypassed but also a wide range of haemodynamic manipulation is necessary. For this reason continuous arterial and central venous pressure monitoring are mandatory. ⋯ All data were analyzed by using Student's 't' test in Statistical Program for Scientific Study (SPSS). From the study, we can conclude that central venous cannulation under local anesthesia in patients for open heart surgery has no significant changes of haemodynamic and humoral stress response in comparison to those of under general anesthesia. So, central venous access device can be placed under local anesthesia supported by premedication and it produces no significant changes in preoperative stress response in patients for open heart surgery.
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Kartagener's Syndrome or Immotile Cilia Syndrome, a variant of Primary Ciliary Dyskinesia (PCD), is a rare autosomal recessive genetic disorder caused by defect in the tiny hair like structure, the cilia lining the respiratory tract (upper and lower), sinuses, eustachian tubes, middle ear and fallopian tubes. Here electron microscopy shows abnormal arrangement of ciliary tubules and patients with Kartagener's syndrome has an absence of dynein arms at the base of the cilia. The inability of cilia to move results in inadequate clearance of bacteria from the air passages, resulting in an increased risk of infection and causing bronchiectasis. ⋯ She had history of chronic cough for 20 years, irregular fever for 20 years and occasional shortness of breath for 5 years. Relevant investigations revealed dextrocardia, situs inversus, bilateral maxillary sinusitis with non pneumatised frontal sinus and bronchiectasis. She was treated with low concentration oxygen inhalation, antibiotic, bronchodilator, chest physiotherapy including postural drainage, vitamins and other supportive treatment.