Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
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Zhonghua Liu Xing Bing Xue Za Zhi · Apr 2017
[Associations between airflow obstruction and the risks of morbidity on major chronic diseases in Chinese adults: a prospective cohort study].
Objective: To examine the prospective associations between airflow obstruction (AFO) and risks of major chronic diseases morbidity in Chinese adults. Methods: Samples of this study were from the China Kadoorie Biobank. A total of 486 996 participants aged 30 to 79 years (mean 51.5 years) at the baseline study, were included after excluding those who self-reported of having heart disease, stroke and cancer at baseline. ⋯ However, each 10% decrease in FEV(1)% P was associated with 7.2% (95%CI: 6.4%-8.0%), 3.6% (95%CI: 3.0%-4.3%) and 10.5% (95%CI: 8.4%-12.6%) increased the risks of ischemic heart disease, cerebrovascular disease and lung cancer respectively. The results were persistant when stratified by smoking status. Conclusion: Higher degree of AFO seemed to be associated with the risks of ischemic heart disease, cerebrovascular disease and lung cancer morbidity among the Chinese adults.
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Zhonghua Liu Xing Bing Xue Za Zhi · Feb 2017
Multicenter Study[Post-marketing surveillance of Tanreqing injection in children: a real world study].
Objective: To evaluate the safety of Tanreqing injection among children in the real world. Methods: A multicenter, large sample, ambispective cohort study, with registration-type clinical safety monitoring. A total of 6 188 inpatients and patients from the emergency units, aged ≤ 14 years who all had been using Tanreqing injection in 59 secondary and tertiary hospitals in China, were recruited between January, 2014 and May, 2015. ⋯ Having histories of allergies to drugs or foods would increase the incidence of ADR. Conclusion:Tanreqing injection caused low incidence of ADR in children. Progams as stratifying high-risk patients and improving administrative management could further increase the safety level of Tanreqing injection.
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Zhonghua Liu Xing Bing Xue Za Zhi · Jan 2017
[Epidemiological characteristics of HBeAg reversion in chronic hepatitis B patients with HBeAg seroconversion in Jiangsu province, 2012-2014].
Objective: To understand characteristics and influencing factors of reversion of HBeAg in chronic hepatitis B patients with HBeAg sero-conversion, and provide epidemiological evidence for the regular management of chronic hepatitis B patients. Methods: From 2012 to 2014, a cohort study was conducted among the chronic hepatitis B patients with sero-conversion of HBeAg in Jiangsu province. Association between participants' demographics, ALT, HBV DNA and incidence of HBeAg reversion was analyzed by Cox regression model. ⋯ Conclusions: There was a certain HBeAg reversion rate in chronic hepatitis B patients with HBeAg sero-conversion. Younger chronic CHB patients with HBeAg sero-conversion and those with higher HBV DNA lever had higher HBeAg reversion rate. Following up and management of chronic CHB patients with HBeAg sero-conversion is important and helpful for the control of hepatitis B.
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Zhonghua Liu Xing Bing Xue Za Zhi · Jan 2017
[Cigarette consumer price and affordability in China: results from 2015 China adult survey].
Objective: To analyze the change of cigarette consumption price, and understand the cigarette affordability in China. Methods: A total of 16 800 households were selected through multi-stage stratified cluster sampling. Then IPAQ was used to randomly select one family member to conduct the survey. ⋯ The calculated median monthly expenditure for cigarettes was 181.4 yuan (RMB). From 2010 to 2015, the proportion of annual expenditure for cigarettes in disposable income per capita declined from 10.5% to 8.8% in urban area and from 21.1% to 17.3% in rural area. Conclusion: During 2010-2015, the purchasing power of Chinese smokers increased in both urban area and rural area due to the decrease of cigarette consumption price.
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Zhonghua Liu Xing Bing Xue Za Zhi · Dec 2016
[Progress of research on azole resistance in Aspergillus fumigatus].
Being an important clinical fungal pathogen, Aspergillus (A.) fumigatus can cause fatal invasive fungal infections. Azoles are the first line drugs in treating various Aspergillus-caused diseases. ⋯ Currently, it has become an important public health issue. In this review, we summarize findings from literature regarding the following areas: the occurrence of azole resistance in A. fumigatus, the molecular mechanisms of resistance, contributing factors for the emergence of azole resistance, evolution of resistant strains and related control and prevention measures.