Fortschritte der Medizin
-
With the enormous increase of alcohol consumption after a period of latency of many years an increase of organic damage is associated, the knowledge of which leads to correct diagnosis. Most often the liver, the central organ of alcohol decomposition, is affected. Many other organs are involved in a specific way. Symptomatology and diagnosis are dealt with in detail.
-
Fortschritte der Medizin · May 1978
Randomized Controlled Trial Comparative Study Clinical Trial Controlled Clinical Trial[Comparative studies on the protective effect of etilefrin and dihydroergotamine in circulatory instability after blood donation].
In 20 female and 40 male subjects with circulatory instability, the response of pulse rate and blood pressure to blood loss and orthostasis was studied under the condition of protective pretreatment with drugs known to improve venous return by increasing the tone of capacitance vessels. Before blood loss (420 ml), in a cross-over double-blind procedure, each subject obtained 10 mg etilefrin or 2 mg dihydroergotamine, both administered orally. ⋯ By comparison of pulse rate and blood pressure taken after pretreatment, the statistical evaluation did not reveal any differences in the effectiveness of one or the other drug on the response to hypovolemic and orthostatic conditions. Patients preferred etilefrin.