Seminars in thrombosis and hemostasis
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Semin. Thromb. Hemost. · Jan 1993
Randomized Controlled Trial Clinical TrialLow molecular weight heparin for the prevention of thromboembolism in outpatients immobilized by plaster cast.
In an open, randomized, prospective, interindividual trial, the incidence of thrombosis with (n = 126) and without (n = 127) LMWH prophylaxis once a day was determined in 253 outpatients immobilized in a plaster cast due to an injury of the lower limb. Furthermore, the influence of possible risk factors on the thrombus formation was determined. The histories of the patients were comparable. ⋯ Crucial risk factors were age over 30 years, obesity, varicose veins, and fractures. Patients without prophylaxis who had fractures developed DVT in 29% in contrast to 11.3% in patients with soft-tissue injuries. This study shows that LMWH prophylaxis should be mandatory for plaster cast immobilized patients regardless of preexisting risk factors for thromboembolism.
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Semin. Thromb. Hemost. · Jan 1993
Review Randomized Controlled Trial Comparative Study Clinical TrialAprotinin in orthotopic liver transplantation.