Zhonghua nei ke za zhi
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Zhonghua nei ke za zhi · Jul 2010
[Stroke volume variation in the evaluation of fluid responsiveness in refractory septic shock].
To evaluate fluid responsiveness by stroke volume variation(SVV) in mechanically ventilated patients with refractory septic shock. ⋯ SVV can accurately predict fluid responsiveness in refractory septic shock patients.
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Zhonghua nei ke za zhi · May 2010
Controlled Clinical Trial[Urinary neutrophil gelatinase-associated lipocalin and urinary interleukin-18 in early diagnosis of acute kidney injury in critically ill patients].
To determine whether urinary neutrophil gelatinase-associated lipocalin (uNGAL) and urinary interleukin-18 (uIL-18) are early markers of acute kidney injury (AKI) in critically ill patients. ⋯ uNGAL and uIL-18 may be the early predictive markers of AKI in critically ill patients.
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Zhonghua nei ke za zhi · May 2010
[The mechanism and pulmonary-protective effects of endothelin-1 receptor antagonist in chronic obstructive pulmonary diseases rat model].
To investigate whether the endothelin (ET) receptor antagonists have protective role in the development of emphysema. ⋯ ET-1 may have an important role in the pathological process of emphysema and ET receptor antagonists protect against the development of emphysema probably by decelerating apoptosis, inhibiting proteolytic enzyme activity and reducing inflammatory cytokine levels.
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Zhonghua nei ke za zhi · Jan 2010
[Diagnostic significance of B-type natriuretic peptide combined with noninvasive cardiac output monitoring in patients with dyspnea.].
To explore the clinical significance of carrying out fast blood B-type natriuretic peptide (BNP) detection together with noninvasive hemodynamic monitoring for pathogenic diagnosis in patients with dyspnea and to assess further the application value of noninvasive cardiac output monitoring in emergency room. ⋯ For patients with dyspnea in the emergency room, the value of BNP concentration of blood plasma to determine cardiac dyspnea is somewhat limited. Appling non-invasive ultrasonic cardiac output monitor in the emergency room to detect CO for identifying the cause of dyspnea is clinically valuable.
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Zhonghua nei ke za zhi · Nov 2009
Randomized Controlled Trial[Adalimumab plus methotrexate for the treatment of rheumatoid arthritis: a multi-center randomized, double-blind, placebo-controlled clinical study.].
To investigate the efficacy and safety of adalimumab plus methotrexate (MTX) for the treatment of rheumatoid arthritis (RA). ⋯ Adalimumab plus MTX is better than single MTX in efficacy for the treatment of RA. Being generally safe and well tolerated, adalimumab plus MTX can significantly increase the response rate, continuously reduce the arthritic signs, symptoms and the inflammatory factors in patients, and also be helpful for reducing disabilities and improving the global quality of life for the patients.