Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Randomized Controlled Trial
Movement observation-induced modulation of pain perception and motor cortex excitability.
The observation of movements increases primary motor cortex (M1) excitability. This exploratory study examined the effects of movement observation on pressure pain threshold (PPT) and transcranial magnetic stimulation (TMS)-indexed corticospinal excitability bilaterally. ⋯ These exploratory findings support the notion that M1 is a robust modulator of pain-related neural networks. This effect might be mediated through modulation of the GABAergic system and appears to differ from what is observed in chronic pain.
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Observational Study
Role of multimodal intraoperative neurophysiological monitoring during positioning of patient prior to cervical spine surgery.
To determine the use of multimodal intraoperative neurophysiological monitoring (IONM) during positioning procedures in cervical spine surgery. ⋯ Multimodal IONM should not only be considered for detecting intra-operative warnings, but also during positioning.
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We aimed to provide additional evidence that brain functional alterations induced by IBS are not limited to local changes but also express at a level of functional integration within related brain regions involved in processing of visceral afferent information and somatic pain. ⋯ Our study may lead to a better understanding of intrinsic functional architecture of brain activity in IBS and highlight the potential for using the ALFF and FC metrics as a disease biomarker.