Biology of the neonate
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Biology of the neonate · Jan 1995
Case ReportsIntrathecal immune response in neonatal Flavobacterium meningosepticum meningitis.
Neonates are predisposed to serious infections such as meningitis, probably due to their immature host reaction to the pathogens. We have studied the intrathecal immune response in 2 newborns with Flavobacterium meningosepticum meningitis. ⋯ In addition, an intrathecal increase and subsequent decrease of both C3dg and TCC (terminal complement complex) were observed in 1 patient. We conclude that immunoglobulin production and complement activation may occur in neonatal CSF.