Biology of the neonate
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Biology of the neonate · Jul 2000
Randomized Controlled Trial Clinical TrialBrain hemodynamic changes in preterm infants after maintenance dose caffeine and aminophylline treatment.
To investigate the acute effects of low-dose caffeine and aminophylline on cerebral blood flow in preterm infants, using both near-infrared spectroscopy (NIRS) and cerebral Doppler ultrasonography. ⋯ Caffeine does not significantly affect brain hemodynamics, while aminophylline induces a significant transient increase in O(2)Hb and HHb concentration and CBV.