Pain medicine : the official journal of the American Academy of Pain Medicine
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Multicenter Study
Pain in postsurgical orthopedic rehabilitation: a multicenter study.
The aim of this study was to quantify and characterize pain in patients undergoing lower limb postsurgical orthopedic rehabilitation and to investigate the impact of pain in slowing or interrupting their rehabilitation. ⋯ In light of the high occurrence and intensity of pain in the sample, and of the significant impact on the rehabilitation program, clinicians should pay more attention to pain, especially neuropathic pain, in postsurgical patients. Tailored pain pharmacological therapy could possibly improve patient compliance during the rehabilitation process and enhance long-term outcomes.
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Randomized Controlled Trial
Randomized, double-blind, placebo-controlled study of the abuse potential of different formulations of oral oxycodone.
The objective of this study was to evaluate the pharmacokinetics and abuse potential of different formulations of oxycodone. ⋯ Intact, orally administered oxycodone CR produced less drug liking and high than IR oxycodone, and required approximately twofold greater doses to produce subjective effects comparable to IR oxycodone.
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The objective of this study was to quantify the network complexity, information flow, and effect of critical-node failures on a prototypical regional anesthesia and perioperative pain medicine (RAPPM) service using social network analysis. ⋯ The RAPPM service entails considerable network complexity and increased hierarchy, but low centrality. The network is at considerable fragmentation risk from even single-node failure.
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Clinical Trial
Home-based aerobic conditioning for management of symptoms of fibromyalgia: a pilot study.
This pilot study was designed to evaluate the impact of a home-based aerobic conditioning program on symptoms of fibromyalgia and determine if changes in symptoms were related to quantitative changes in aerobic conditioning (VO(2) max). ⋯ Patients suffering from fibromyalgia who can participate in an aerobic conditioning program may experience physiological and psychological benefits, perhaps with improvement in symptoms of fibromyalgia, specifically pain ratings. More definitive trials are needed, and this pilot demonstrates the feasibility of the quantitative VO2 max method. Subjects who experience significant perceived disability and negative affective symptoms are not likely to maintain a home-based conditioning program, and may need a more comprehensive interdisciplinary program offering greater psychological and social support.
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Intradiscal high-pressure injection of saline (IDHP) is a noninvasive procedure for a lumbar intervertebral disc extrusion and an alternative treatment to surgery, such as microendoscopic discectomy (MED). The purpose of this study was to compare the representative outcomes of IDHP with MED in terms of pain relief, reduction of disability, and risk of complications. ⋯ IDHP produced significant effects on patients with radicular pain, leading to the improvement of VAS and JOA. Although IDHP displayed slightly less efficacy than MED, IDHP appears to be an alternative as a nonoperative treatment for a lumbar intervertebral disc extrusion.