Sheng wu gong cheng xue bao = Chinese journal of biotechnology
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Sheng Wu Gong Cheng Xue Bao · Mar 2019
Review[Baeyer-Villiger monooxygenases in the biosynthesis of microbial secondary metabolites].
Baeyer-Villiger monooxygenases, a well-studied class of flavin-dependent enzymes, catalyze the conversion of ketones to lactones or esters and the oxygenation of heteroatoms, which possesses great practical prospect in synthetic chemistry and biocatalysis. In this review, we focus on Baeyer-Villiger oxidations involved in biosynthesis of microbial secondary metabolites and discuss the characteristics of these Baeyer-Villiger oxidations and Baeyer-Villiger monooxygenases, to provide reference for the protein engineering of Baeyer-Villiger monooxygenases.