Emergency medicine journal : EMJ
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Randomized Controlled Trial
A double-blind, randomised, placebo-controlled trial of oral midazolam plus oral ketamine for sedation of children during laceration repair.
To compare the efficacy of oral midazolam alone with a combination of oral midazolam and ketamine in children requiring laceration repair. ⋯ The trial was registered in www.clinicaltrials.gov as NCT01470157.
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Randomized Controlled Trial Multicenter Study
STOP!: a randomised, double-blind, placebo-controlled study of the efficacy and safety of methoxyflurane for the treatment of acute pain.
To evaluate the short-term efficacy and safety of methoxyflurane for the treatment of acute pain in patients presenting to an emergency department (ED) with minor trauma. ⋯ The results of this study suggest that methoxyflurane administered via the Penthrox inhaler is an efficacious, safe, and rapidly acting analgesic.