Brain and behavior
-
Multicenter Study
Genetic variation and cognitive dysfunction in opioid-treated patients with cancer.
The effects of single-nucleotide polymorphisms (SNPs) on the cognitive function of opioid-treated patients with cancer until now have not been explored, but they could potentially be related to poor functioning. This study aimed at identifying associations between SNPs of candidate genes, high opioid dose, and cognitive dysfunction. ⋯ The findings did not support influence of those SNPs analyzed to explain cognitive dysfunction in opioid-treated patients with cancer.