Clinical biochemistry
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Clinical biochemistry · Jul 2019
Analytical characterization of the Siemens Dimension EXL high-sensitivity cardiac troponin I assay.
Siemens Healthcare Diagnostics has four commercially available assays on different analytical platforms using different methodologies to generate signal. We assessed the analytical performance of the Dimension EXL hs-cTnI assay (LOCI method) across different matrices and compared it to two different acridinium ester-based hs-cTnI assays (ADVIA Centaur and Abbott ARCHITECT). ⋯ The Siemens EXL hs-cTnI assay meets the analytical criteria for a high-sensitivity assay, with assay specific cutoffs important to maximize clinical performance.
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Clinical biochemistry · Jul 2019
ReviewData science, artificial intelligence, and machine learning: Opportunities for laboratory medicine and the value of positive regulation.
Artificial intelligence (AI) and data science are rapidly developing in healthcare, as is their translation into laboratory medicine. Our review article presents an overview of the data science domain while discussing the reasons for its emergence. We also present several perspectives of its applications in clinical laboratories, along with potential ethical challenges related to AI and data science.