Journal of cosmetic dermatology
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Randomized Controlled Trial Multicenter Study Comparative Study
A multi-center comparative efficacy and safety study of two different hyaluronic acid fillers for treatment of nasolabial folds in a Chinese population.
Nonsurgical injectable treatments, including hyaluronic acid (HA) fillers, are increasingly used in Asian patients. ⋯ Similar to Restylane, Restylane Lyft was effective and well tolerated for treatment of moderate to severe NLFs in this Chinese population.
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Randomized Controlled Trial
Topical skin therapies in subjects undergoing full facial rejuvenation.
Cosmeceutical therapies including face washes, moisturizers, chemical peels and antioxidant formulations are intended to improve the esthetic appearance of skin. The use of these products as adjuncts to full facial rejuvenation with hyaluronic acid filler and abobotulinumtoxinA may improve cosmetic and socio-esthetic outcomes. ⋯ The cosmeceutical therapies used in this study in combination with abobotulinumtoxinA and hyaluronic acid filler improved subjects' skin quality, self-esteem, and projected first impressions. Larger studies are needed to determine the most efficacious combination of topical skin therapies with facial rejuvenation therapy.
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Comparative Study Clinical Trial
Effects of four soaps on skin trans-epidermal water loss and erythema index.
Various tests have been carried out to determine the irritant potential of soaps/cleansers. ⋯ Traditional alkaline soap increased TEWL and skin erythema, which are signs of prolonged damage to the skin barrier. However, the effects of other formulations were transient, and TEWL returned to baseline at 72 hours. Creamy soap even showed a relative protective effect (decrease in erythema index compared to baseline), probably due to the lanolin content of the formulation.