Articles: analgesia.
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Pharmaceutical research · Mar 1998
Comparative StudyControlled release gel of ibuprofen and lidocaine in epidural use--analgesia and systemic absorption in pigs.
Reduction of the frequency of injections and localization of the absorption of drug molecules to the injection site would be of great advantage in epidural pain treatment. The epidural use of a controlled release gel of lidocaine and ibuprofen was studied. ⋯ These results demonstrate poloxamer gel to be a promising controlled-release, injectable epidural formulation for the management of pain.
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To ascertain patients' recall of the risks of labor epidural analgesia from a discussion of informed consent during active labor. ⋯ Recall of risks by parturients is similar to the recall of risks by other patients, and it does not appear to be affected by parity or the reported level of pain.
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Two hundred patients completed a questionnaire about their experiences of patient-controlled analgesia. The questionnaire covered the following topics: pre-operative information, reasons for pressing and not pressing the button, pain relief, side-effects, safety, advantages and disadvantages of patient-controlled analgesia, worries associated with its use and control over pain. ⋯ However, more detailed questions revealed side-effects and fears that constrained its use and hence patients' ability to control pain. Control is predominantly a feature of the professional's view of patient-controlled analgesia, rather than the patient's experience of this analgesic technique.
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Acta Anaesthesiol. Sin. · Mar 1998
Case ReportsManipulation of epidural catheter that has migrated restores adequate postoperative analgesia--a case report.
The use of epidural anesthesia and analgesia is ordinary in patients undergoing total knee replacement (TKR). As many as 23% of epidural anesthetics may not provide satisfactory analgesia for women in labor. ⋯ We reported a case in whom the in-place epidural catheter which functioned well for surgical anesthesia previously migrated to an intervertebral foramen postoperatively and led to failure of providing post-operative analgesia. With deliberate manipulation we succeeded in restoring its function and analgesia showed up again.