Articles: disease.
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J Coll Physicians Surg Pak · Oct 2020
Observational StudyOpportunistic Infection in Hospitalised Patients with Inflammatory Bowel Disease.
To investigate the incidence, clinical features, and risk factors of opportunistic infections in elderly patients with inflammatory bowel disease (IBD). ⋯ Hospitalised elderly IBD patients, receiving corticosteroids, immunosuppressive, and biological agents, are at higher risk for infection. The symptoms of opportunistic infections in elderly patients are atypical, but they are prone to multiple infections with poor prognosis. Key Words: Elderly patients, Inflammatory bowel disease, Opportunistic infection, Systemic inflammation reaction syndrome.
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J Coll Physicians Surg Pak · Oct 2020
Observational StudyPulmonary Functions and Factors Affecting Them in Patients with Chronic Kidney Disease.
To determine the pulmonary functions in patients with chronic kidney diseases (CKD) and factors affecting them. ⋯ Pulmonary functions were abnormal in almost half of the patients and restrictive lung disease was the most common pattern in these patients. Factors affecting the pulmonary functions were progression of CKD, falling hemoglobin level, monthly income and education. Drop in GFR and anemia had negative correlation and age had positive correlation with pulmonary functions. Key Words: CKD, Pulmonary functions, Restrictive lung disease, GFR, Anemia.
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Vaccination practices in Germany are driven by scientific developments and a complex regulatory environment. Some important developments in 2019/20 are described here: Work-related vaccination recommendations for measles, rubella, and chickenpox have been streamlined and expanded. In addition, measles vaccination or documentation of immunity is now mandatory for employment at and attendance of many institutions, specifically including day care centers and schools. ⋯ After years of development and clinical studies the first vaccine against Ebolavirus disease has been licensed by EMA in November and by FDA in December 2019. More than 150 SARS-CoV-2 vaccine candidates are being developed with massive financial support, several phase 1/2 trials have started. A licensed vaccine may actually be available in 2021 and thus dramatically faster compared to any other modern vaccine development.
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J Coll Physicians Surg Pak · Oct 2020
Case ReportsA Case of Systemic Lupus Erythematosus with Malignant Pleural Mesothelioma in a 42-year Woman.
Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease characterised by inflammation. Malignant pleural mesothelioma (MPM) is a highly invasive malignant tumor derived from pleural mesothelial cells. Here, we report a case of SLE with MPM. ⋯ We should pay attention to pleural effusion when diagnosing SLE. If possible, a pleural biopsy should be performed to reduce misdiagnosis and missed diagnosis. Key Words: Pleural effusion, Systemic lupus erythematosus (SLE), Mesothelioma.