Articles: disease.
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Transfusion-dependent β-thalassaemia (TDT) is a severe disease, resulting in lifelong blood transfusions, iron overload, and associated complications. Betibeglogene autotemcel (beti-cel) gene therapy uses autologous haematopoietic stem and progenitor cells (HSPCs) transduced with BB305 lentiviral vector to enable transfusion independence. ⋯ Bluebird Bio, Somerville, MA, USA.
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Dengue fever is a common infectious disease in the tropical and subtropical zones, with more than 100 million symptomatic cases per year. Mosquitoes of the genus Aedes (Aedes aegypti, Aedes albopticus) are vectors of the disease, and their spread has led to rising case numbers around the world. Physicians in Europe, too, are increasingly being confronted by this challenge. ⋯ Climate change and global mobility have led to a worldwide increase in dengue fever. The disease only rarely takes a severe course. In such cases, rapid symptomatic treatment as needed is the key to the avoidance of severe complications.
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Modern treatment strategies have markedly improved the chances of survival for patients with cancer. As the population ages, cancer is becoming more common, as is chronic kidney disease (CKD). CKD increases the risk of cancer; conversely, cancer treatments can cause CKD. ⋯ Patients who have CKD, are on dialysis, or have undergone kidney transplantation make up a considerable fraction of persons being treated for cancer, and they need interdisciplinary treatment.
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Pol. Arch. Med. Wewn. · Nov 2024
Prognostic value of preoperative echocardiography in predicting myocardial injury after open abdominal aortic surgery.
Abdominal aortic aneurysms (AAAs) and peripheral arterial and aortic diseases (PAAD) are associated with increased risk of myocardial injury after noncardiac surgery (MINS). ⋯ Our study suggests that routine preoperative TTE may have a low but possible value in the prediction of MINS among patients undergoing high-risk vascular surgery.