Articles: sars-cov-2.
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Current drug targets · Jan 2020
ReviewFacts and myths: Efficacies of repurposing chloroquine and hydroxychloroquine for the treatment of COVID-19.
The emergence of coronavirus disease 2019 (COVID-19) is caused by the 2019 novel coronavirus (2019-nCoV). The 2019-nCoV first broke out in Wuhan and subsequently spread worldwide owing to its extreme transmission efficiency. The fact that the COVID-19 cases and mortalities are reported globally and the WHO has declared this outbreak as the pandemic, the international health authorities have focused on rapid diagnosis and isolation of patients as well as search for therapies able to counter the disease severity. ⋯ Repurposing anti-malarial drugs and chloroquine (CQ)/ hydroxychloroquine (HCQ) have shown efficacy to inhibit most coronaviruses, including SARS-CoV-1 coronavirus. These CQ analogues have shown potential efficacy to inhibit 2019-nCoV in vitro that leads to focus several future clinical trials. This review discusses the possible effective roles and mechanisms of CQ analogues for interfering with the 2019-nCoV replication cycle and infection.
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Rocz Panstw Zakl Hig · Jan 2020
Covid-19: a survey on knowledge, awareness and hygiene practices among dental health professionals in an Indian scenario.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or COVID-19) continues to spread globally. It has become a major cause of concern for health care professionals all over the world. ⋯ The findings of the present study showed that some notable deficiencies in knowledge existed among dental professionals regarding some vital aspects of COVID-19. Therefore, there is an urgent need for improving dentists’knowledge via health education and training programs. Further studies on the subject are also warranted once the situation normalizes.
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Report on the implementation of assistance protocols in the face of the COVID-19 pandemic developed in the surgical center of a large university hospital in Rio Grande do Sul. ⋯ With the established routines and a large number of trained professionals, it was possible to observe a better preparation of the multidisciplinary team in face of the needs imposed by the new coronavirus.
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To report the use of auriculotherapy to optimize emergency workers' health during the COVID-19 pandemic. ⋯ In the report of auriculotherapy, the description of its application and its positive and negative points in relation to professionals working in the pandemic scenario were considered and its continuity was requested.
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With social distancing being a key preventative measure of COVID-19, proper provision of healthcare services becomes a challenge as healthcare professionals are concerned about the risk of potential infection. Telemedicine, a practice that uses telecommunication networks for the delivery of healthcare services and medical education, has been adopted by several countries and has shown to provide positive outcomes. This concept is poorly practiced in African Countries compared to other countries of the world. This paper reiterates the need for the expansion of telemedical systems in Africa for the dual goals of COVID-19 prevention and provision of quality healthcare services to people.