Articles: respiratory-distress-syndrome.
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Anesteziol Reanimatol · Sep 1992
[The effect of a nitroglycerin infusion on the hemodynamics, extravascular lung water and gas exchange in patients with adult respiratory distress syndrome].
Nine patients with adult respiratory distress syndrome, stage III, secondary to diffuse peritonitis have been examined. The patients were subject to pulmonary artery and aorta catheterization. ⋯ Selective hypotension in the pulmonary circulation was performed using an infusion of nitroglycerin solution. Despite differences in the response of patients with ARDS to nitroglycerin, when the drug was injected with optimal positive end-expiratory pressure, it promoted an increase in O2 delivery, normalization of pulmonary hemodynamics and a decrease in extravascular pulmonary water.
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Bronchopulmonary dysplasia (BPD) is both a significant clinical problem associated with neonatal intensive care and a sign of the success of that care. It can best be understood in the context of the historical continuum of improving survivability for prematurely born infants. ⋯ All the molecular-biologic and technologic approaches used in the past 25 years have not clearly reduced the overall incidence of BPD. It would seem time to approach seriously the problem of decreasing the overall incidence of BPD by decreasing the incidence of premature birth in the United States.
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J. Heart Lung Transplant. · Sep 1992
Case ReportsSuccessful lung transplantation for posttraumatic adult respiratory distress syndrome after extracorporeal membrane oxygenation support.
A severe adult respiratory distress syndrome after bilateral lung contusion was successfully treated by extracorporeal membrane oxygenation and subsequent double-lung transplantation in a 19-year-old man. The patient is fully rehabilitated 1 year after transplantation.
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Comparative Study
Relationship of oxygen consumption and oxygen delivery in surgical patients with ARDS.
Previous studies have described oxygen delivery (DO2) and oxygen consumption (VO2) relationships in patients with ARDS and other acute diseases that suggest occasions when VO2 may be dependent on the supply of oxygen, ie, DO2. We studied 127 postoperative patients who developed ARDS to evaluate the relationship of DO2 to VO2. We found a weak correlation between DO2 and VO2 in the total series (r = 0.49) as well as in several clinical subgroups of patients with ARDS. ⋯ We also examined the DO2/VO2 data of individual patients with ARDS to identify instances where flow-dependent VO2 patterns developed into flow-independent VO2 patterns. We were able to identify an apparent plateau in the DO2/VO2 relationships in 29/50 (58 percent) patients where multiple measurements were obtained over a short period of time. Our data are consistent with the concept that the DO2/VO2 relationship in acutely ill early postoperative patients with and without ARDS is affected by antecedent circulatory problems that may lead to tissue hypoxia and tissue oxygen deficiencies that are manifest by flow dependency.