This small study of patients having lumbar spinal fusion was unable to show a statistically significant reduction in postoperative opioid consumption in those receiving epidural bupivacaine/opioid versus those receiving a sham epidural.
This small, pilot study suggests that isoflurane may be more commonly associated with post-operative cognitive dysfunction than desflurane in older patients.
Nice summary, seems like common sense with very useful number needed to harm data, though from personal experience surprising the NNH for itching was lower for Fentanyl than Morpine